Intra-patient viral evolution in polyomavirus-related diseases
نویسندگان
چکیده
منابع مشابه
Viral diseases and human evolution.
The interaction of man with viral agents was possibly a key factor shaping human evolution, culture and civilization from its outset. Evidence of the effect of disease, since the early stages of human speciation, through pre-historical times to the present suggest that the types of viruses associated with man changed in time. As human populations progressed technologically, they grew in numbers...
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Across the whole dataset, eleven cases from six animals were found in which three separate nucleotides were observed at a single locus. However, none of the alleles in these cases were identified as potentially non-neutral using the single-locus version of our method. In other datasets, where greater evidence of non-neutrality was found for cases of multiple alleles at a locus, our method could...
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While studying the virome of the skin surface of a patient with a Merkel cell carcinoma (MCC) by using unbiased, high-throughput sequencing, we identified a human polyomavirus nearly identical to human polyomavirus 9, a virus recently reported in blood and urine of renal transplantion patients and closely related to the African green monkey lymphotropic polyomavirus. Specific PCR analysis furth...
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ژورنال
عنوان ژورنال: Philosophical Transactions of the Royal Society B: Biological Sciences
سال: 2019
ISSN: 0962-8436,1471-2970
DOI: 10.1098/rstb.2018.0301